Introduction  The attachment and growth of Marine organisms in the water transfer system reduces the effective diameter of the water pipeline and the flow of seawater. In order to ensure the normal water transfer, it is necessary to prevent and control Marine organisms.

  Method  Take a nuclear power plant as an example, this paper studied the Marine organisms control scheme of long-distance water transfer project through the field investigation and analysis of Marine organisms at the water intake and the dynamic simulation test.

  Result  The results show that NaClO and non-oxidizing biocide add alternately at multiple points, and the control effect of Marine organisms is good.

  Conclusion  The purpose of this paper is to provide a reference for the future Marine organisms control of similar projects.