Introduction  The paper aims to sovle the sub-grade problems cause by complex karst and soil cave foundation, design problems in karst and soil cave foundation treatment design, construction problems often occurred in power plant projects, such as advanced drilling, bored pile and PHC pile construction difficult problems etc..

  Method  To describe the relevant karst and soil cave treatment key technologies, including treatment principles, treatment methods (including filling method, crossing method, pile foundation method), we analyzed and compared the relevant specifications, costs and practical engineering experience.

  Results  The results we obtained is the solutions to the difficult problems in the treatment of karst and soil cavern foundation and the problems that are easy to occur in the punching construction of pile foundation of karst cavern foundation and the emergency response plan.

  Conclusion  Finally, several treatment methods of karst foundation in power plant are suggesed, which can be used as reference for similar projects.