Abstract: By the analysis on F advanced class combined cycle power plant operation conditions, sizing calculation method of air compressor and air receiver is investigated as per gas turbine special requirements. The calculated results show that 4 air compressors with capacity of 25 Nm³/min and 4 receivers with capacity of 30 m³ can make units running in safe condition and meet the minimum static investment requirement. The optimization design of the compressed air system has improved plant service air system to enable the air receiver to be served for the instrument air system during emergency condition. With the engineering practice in this project, it will provide reference to future similar engineering calculation for compressed air system.