Abstract: During July and September each year, typhoon and rain often happen in Pearl River Estuary at Guangdong Province, where the typhoon from Western Pacific and South China Sea often lands. According to the geographical location and natural condition of Guangdong Province, this paper describes the typhoon distribution in this area, design of turbine's anti typhoon strategy and prevention measurements needed to consider during design of wind farm. From view of design, it also introduces some typhoon prevention measurements for new offshore wind farm. It provides a reference for the construction of offshore wind farm where typhoon often happens.